Spice it up with Cultured Hot Sauce, boost your immunity
Sep 20, 2014
Powerful Food, Cultured Hot sauce
Hot peppers, garlic, onions. This cultured hot sauce is a probiotic, anti viral, anti bacterial, anti fungal, anti-oxidant immune boosting food.
You need just 3 thing chilies, salt and time, then you can think about the addition of garlic, and /or onions to provide a depth to the sauce. It's optional to add unrefined cane sugar to provide a sweetness, I didn't.
Lacto-Fermented hot chili sauce is explosive with heat and packed full with food enzymes, beneficial bacteria, vitamin C and carotene.
Fermented foods are foods that have been through a process of lactofermentation in which natural bacteria feed on the sugar and starch in the food creating lactic acid. This process preserves the food, and creates beneficial enzymes, b-vitamins, Omega-3 fatty acids and various strains of probiotics.
Ingredients
You need just 3 thing chilies, salt and time, then you can think about the addition of garlic, and /or onions to provide a depth to the sauce. It's optional to add unrefined cane sugar to provide a sweetness, I didn't.
Lacto-Fermented hot chili sauce is explosive with heat and packed full with food enzymes, beneficial bacteria, vitamin C and carotene.
Fermented foods are foods that have been through a process of lactofermentation in which natural bacteria feed on the sugar and starch in the food creating lactic acid. This process preserves the food, and creates beneficial enzymes, b-vitamins, Omega-3 fatty acids and various strains of probiotics.
Natural fermentation of foods has also been shown to preserve nutrients in food and break the food down to a more digestible form. This, along with the bevy of probiotics created during the fermentation process could explain the link between consumption of fermented foods and improved digestion.
3 pounds fresh chili peppers
4 to 6 cloves garlic, peeled and minced
4 to 6 cloves garlic, peeled and minced
3 onions
2 tablespoons unrefined cane sugar, optional
2 teaspoons unrefined sea salt
vegetable starter culture dissolved in 1/4 cup water, or 1/4 cup fresh whey (optional)
2 tablespoons unrefined cane sugar, optional
2 teaspoons unrefined sea salt
vegetable starter culture dissolved in 1/4 cup water, or 1/4 cup fresh whey (optional)
Method
Snip the stems from the chilies, but leave their green tops intact.
Combine all all ingredients in a food processor, or mince by hand, until chopped to a fine pasty texture.
Spoon the chili paste into a glass mason jar and allow it to fermented, covered, at room temperature for five to seven days.
After the chili paste has bubbled and brewed for about a week, set a fine-mesh sieve over a mixing bowl and spoon the fermented chili paste into the sieve. With a wooden spoon, press the chili paste into the sides of the sieve so that the sauce drips from the sieve into the waiting mixing bowl.
Once you’ve pressed and pushed the chili sauce through the sieve, pour the sauce from the bowl into jar or bottle and store in the refrigerator. The sauce will keep for several months.
Snip the stems from the chilies, but leave their green tops intact.
Combine all all ingredients in a food processor, or mince by hand, until chopped to a fine pasty texture.
Spoon the chili paste into a glass mason jar and allow it to fermented, covered, at room temperature for five to seven days.
After the chili paste has bubbled and brewed for about a week, set a fine-mesh sieve over a mixing bowl and spoon the fermented chili paste into the sieve. With a wooden spoon, press the chili paste into the sides of the sieve so that the sauce drips from the sieve into the waiting mixing bowl.
Once you’ve pressed and pushed the chili sauce through the sieve, pour the sauce from the bowl into jar or bottle and store in the refrigerator. The sauce will keep for several months.
source
blog.siffordsojournal.com
ybertaud9.wordpress.com/
Raw chocolate,coconut cannabis oil brownies
Sep 19, 2014
Todays quick finish for a sweet moment with health benefits... Cashew, hazelnuts walnuts, hemp seeds (peeled), dates, raisins, raw honey, raw chocolate powder, vanilla, salt, cannabis coconut oil, blend it and place in a baking dish, leave in the fridge for 1-2 hours and its brownie time!
Natural Medicine: Can you cure yourself with Cannabis Infused Coconut Oil
Sep 18, 2014
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Oh Yes I did. I made my own cannabis coconut oil. You can too, and this is how and why you should......
According to philstar.com medical researchers have proven that coconut oil makes you less hungry, contains ketones that reduce seizures, improves blood cholesterol, burns fat, and boosts brain function in Alzheimer’s patients.
But more importantly, scientists have uncovered the potential of coconut oil to aid cannabis (marijuana) in the fight against cancer.
Former US Surgeon General Dr. Joycelyn Elders wrote in a a report on March 26, 2004 titled “Myths about Medical Marijuana” and published in the Providence Journal: “The evidence is overwhelming that marijuana can relieve certain types of pain, nausea, vomiting, and other symptoms caused by such illnesses as multiple sclerosis, cancer, and AIDS — or by the harsh drugs sometimes used to treat them. And it can do so with remarkable safety. Indeed, marijuana is less toxic than many of the drugs that physicians prescribe every day.”
But relieving pain and symptoms is just the tip of the iceberg. Medical marijuana is said to slow the onset of Alzheimer’s disease and moderate autoimmune disorders, including multiple sclerosis, inflammatory bowel disease, and rheumatoid arthritis. Scientists believe that, coupled with coconut oil, the healing potential of medical marijuana is amplified even more.
Medical marijuana capsules, infused in coconut oil, are an alternative way to therapeutically use cannabis without having to inhale it through smoking. Infusing cannabis into coconut oil also allows for easy entry into the liver where it can be rapidly processed.
The Alternative Daily reports that coconut oil is used because of its high amount of essential fatty acids, which makes it a good binding agent for the cannabinoids. Half of the fat in coconut oil is comprised of lauric acid. Lauric acid is called a miracle ingredient because in the body it is converted to monolaurin, which is a potent antiviral, antibacterial, and anti-protozoal substance. Monolaurin can destroy lipid-coated viruses including measles, flu, HIV, herpes, and a number of pathogenic bacteria.
More and more medical researchers are intrigued by this powerful combination of cannabis and coconut oil.
Ingredients
cannabis leaves trim and some buds
coconut oil
Method
If you are using fresh weed you really should decarboylate it first.
" When you smoke weed, the THCA molecule loses its carboxylic group (COOH) in the form of water vapor and carbon dioxide and becomes THC. Long story short, THCA becomes THC and your cannabis becomes psychoactive. This process is called decarboxylation or decarbing.When you smoke or vaporize marijuana, the cannabis is decarbed by the heat. If you ingest cannabis and want the full psychoactive effect, you need to first decarb your cannabis before you cook with it." according to thestonerscookbook.com
How to Decarboxylate
The goal of cannabis decarbing is to activate the cannabinoids with minimal vaporization of cannabinoids or terpenes (cannabinoids responsible for how cannabis smells). The lower the temperature, the longer the decarb time required, but less loss of terpenes due to vaporization. Heating your cannabis in a closed container will also help reduce the loss of cannabinoids and terpenes by trapping any vapor and allowing it to be reabsorbed into the cannabis material as it slowly cools down after being decarbed. In a covered oven dish heat up you cannabis (leave,stems,buds if using) in the oven at abut 115 Celsius or 245 Fahrenheit for about 30-60min.
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The Infusion
You can infuse your coconut oil using a stove top and a double broiler, at a very low heat, the water should just be below boiling and the coconut oil should not smoke. Once you have warmed your liquid coconut oil, add your ground up plant matter. There is no need to add seeds, but stems are welcome! The strength and ratio of oil to cannabis is variable and up to your discretion. I used a 1:1 ratio, with enough coconut oil to cover the amount of cannabis in the bowl.
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THC activates as low as 160 degrees F, and it starts breaking down at 350 degrees F, which is also the smoking point of coconut oil. Once the THC begins breaking down you are receiving less benefits.The goal is to keep the oil just below a simmer with occasional stirring
coconut oil
After about an hour, (or 5 if you have the time) you should notice the oil has turned green – this let’s you know it is done. .
When you are ready to jar the oil, prepare a large mason jar with a secure cheesecloth around the lid – a tight rubber band will do the trick. Then pour the green oil slowly into the jar, let it cool down and keep in the fridge.
This oil can be used in all kinds of recipes especially the raw food desserts work very well.
source:
www.medicaljane.com
greenstyleconsulting.us
Organic Raw Orange Chocolate Balls
Sep 17, 2014
Don't toss out those organic orange peels make these great fast snack balls. Use organic ingredients.....toss it in the food processor......
Orange zest, raw chocolate powder, oats, cashews, dates, raisins, vanilla, coconut oil or (cannabis coconut oil). Place everything in the food processor until doughy then make some balls.
Try not to eat them all in one go....
How to combine herbs to make your own tinctures
Sep 14, 2014
Tinctures are amazing little gems for maintaining a healthy robust body (both chronic and acute situations), and they’re easy to make. Think of tinctures as basically herbal tea on steroids. You get a strong dose of the healing powers of plants in a tiny (convenient) amount (some say that two droppersful of tincture equals an 8 ounce cup of herbal tea). Tinctures are highly assimilable especially if you can stand to put them, straight, under your tongue for a few moments. Tinctures made using alcohol preserve active plant constituents. Another big selling point is that alcohol based tinctures last for years (pretty much indefinitely so long as they’re stored in a cool dark place. No refrigeration is necessary for alcohol based tinctures).
DIGESTIVE: comfrey, marshmallow, mint(s), ginger, basil, fennel, dill, catnip, chamomile, cardamom, yellow dock, meadowsweet, orange peel, rosemary, calendula, cayenne, lemon balm, licorice root.
ENERGY: mint(s), rosemary, ashwaganda, rhodiola, licorice root, nettles, oats, yellow dock.
CALM / SLEEP: California poppy, catnip, chamomile, betony, hawthorn, hops, cowslip, lavender, lemon balm, lime blossoms, kava kava, passion flower, skullcap, valerian.
JOINTS / INFLAMMATION: ginger, garlic, turmeric, cayenne, red clover, celery seed, nettle, oats.
PREGNANCY / LABOR: raspberry leaf, squaw vine, cramp bark, false unicorn, blue cohosh. Seek the help from your midwife for proper usage, if at all, of these herbs. Some might be appropriate during certain trimesters.
ADRENALS: licorice root, lingstrum, borage, dandelion, nettle.
SKIN: comfrey, dandelion, calendula, aloe, burdock, echinacea, chickweed, goldenseal, schizandra, honeysuckle.
PARASITES: oregano, pumpkin seeds, wormwood (not for use during pregnancy), cucumber seeds
LONGEVITY: rhodiola, bilberry, damiana, ginkgo biloba, gotu kola, ashwaganda, astragalus root, nettle, schizandra.
LYMPH: cleavers, echinacea, poke root.
KIDS: California poppy, catnip, chamomile, lemon balm, mint(s). Many more are fine for kids, I’m simply listing some popular ones.
FEVER: catnip, yarrow, boneset.
EXTERNAL TRAUMA (see also “skin” above): comfrey, yarrow, calendula.
COLDS / VIRUSES / IMMUNITY: cinnamon, hibiscus, ashwaganda, astragalus root, rose hips, myrrh, lemon balm, garlic, oregano, thyme, mint(s), echinacea, elder, lingstrum, red clover, self heal, boneset, yarrow (good for fever), mullein, turmeric, licorice root.
COUGH: elecampane root, comfrey, coltsfoot, white horehound (comfrey + coltsfoot + white horehound particularly good for bronchial issues), red clover, fennel, thyme, licorice root, cowslip, bittersweet, squill, mullein, marshmallow, wild cherry bark, balm of Gilead, black cohosh, and the following are helpful for whooping cough: mouse ear + mullein + white horehound + wild cherry bark + coltsfoot.
FEMALE (SEX, HORMONES, REPRODUCTION): vitex (turns out this isn’t a fit for me), ashwaganda, nettle, red clover, raspberry leaf, rosemary, hops (increases milk production), damiana, schizandra, yellow dock, licorice root, yarrow, ginger, dong quay, black cohosh.
MEN HORMONE HEALTH: saw palmetto, ginseng(s), damiana
HEADACHE: skullcap, basil, horseradish (sinus headaches), lavender, mint(s), cowslip (sinuses).
BRAIN: ashwaganda, rosemary, rhodiola, ginkgo biloba, gotu kola, bilberry.
CIRCULATORY / HEART: cayenne, hawthorn, ginger, rosemary, cinnamon, garlic, ginkgo biloba, dandelion, burdock
ACUTE PAIN: valerian, turmeric
Another way to see this list is by the various ways even one herb can help. See which herbs give you the biggest bang for your buck.
COMFREY: digestion, skin, cough
MINT(S): digestion, energy, headaches, kids
GINGER: digestion, inflammation, circulatory
ASHWAGANDA: brain, longevity, hormones, colds / immunity, energy
SKULLCAP: headaches, sleep
LICORICE ROOT: female hormones, cough, digestive, energy, adrenals
RED CLOVER: inflammation, immunity, cough, female hormones
Rosemary Gladstar’s good tincture taking advice is the following, and I will repeat that I am not a medical professional… please do your own research or speak with a professional:
- Acute health problems: 1/4 to 1/2 teaspoon of tincture taken every hour for a maximum of 6 teaspoons daily. Reminder that this dosage is for acute problems and short term.
- Chronic health problems: 1/2 to 1 teaspoon of tincture taken 2-3 times daily for a maximum of 3 teaspoons daily. This recommendation also comes with a note to cycle the usage. Perhaps 5 days on and 2 days off or 2 to 3 weeks on and 1 week off. You’ll have to experiment yourself and seek professional guidance as needed.
- Treating children: if the dose for an adult is one teaspoon of tincture, then a child of less than one year old (2 to 5 drops), a child of 1 to 2 years (5 to 8 drops), child of 2 to 6 years (10-15 drops), and a child of 6 to 12 years (15 to 30 drops).
source http://kristensraw.com/
Are you feeling tired and stressed? Enhance your Health with these Top 10 Superfoods
Sep 12, 2014
Reishi is Queen of the Medicinal Mushrooms. Reishi is the most well-studied herb in the history of the world. She has been the most revered herbal mushroom in Asia for over 2,000 years. The Daoists consider Reishi an “elixir of immortality” that is celebrated for its ability to significantly improve the functioning of the immune system by protecting us from the onslaught of viruses, bacteria, unwanted guests, pollution, chemicals, molds, and the toxicity that we are often subjected to in our world. Reishi helps build up our “stress defense shield” creating feelings of well-being within in spite of outer stresses.
2. Chaga Mushroom
Chaga is the King of the Medicinal Mushrooms. It contains the highest amounts of anti-tumor compounds of any herb. These compounds are in the form of betulin, betulinic acid and lupeol, which are powerful anti-mutagenic compounds naturally present in the white part of the birch tree’s bark (in which the chaga typically grows). Chaga is also extremely high in nourishing phytochemicals, nutrients, and free-radical scavenging antioxidants, especially melanin. Chaga is second only to cacao in antioxidant content. Chaga is the most powerful cancer-fighting herb known.
Chaga is the King of the Medicinal Mushrooms. It contains the highest amounts of anti-tumor compounds of any herb. These compounds are in the form of betulin, betulinic acid and lupeol, which are powerful anti-mutagenic compounds naturally present in the white part of the birch tree’s bark (in which the chaga typically grows). Chaga is also extremely high in nourishing phytochemicals, nutrients, and free-radical scavenging antioxidants, especially melanin. Chaga is second only to cacao in antioxidant content. Chaga is the most powerful cancer-fighting herb known.
3. Gynostemma
According to the scientific herbal research being conducted in the People’s Republic of China, gynostemma has been identified as the most medicinal of all the Chinese herbs. It contains 120 saponins (immune modulating molecules that are fat soluble on one side of the molecule and water soluble on the other side) — all of which possess unique and specific health-giving properties. Gynostemma is a true tonic — you can take it or make tea out of it nearly every day with benefits that accrue the more you consume it. Gypenoside 49 (49th of the 120 saponins) has been identified as a telomerase activator that youthens us genetically.
According to the scientific herbal research being conducted in the People’s Republic of China, gynostemma has been identified as the most medicinal of all the Chinese herbs. It contains 120 saponins (immune modulating molecules that are fat soluble on one side of the molecule and water soluble on the other side) — all of which possess unique and specific health-giving properties. Gynostemma is a true tonic — you can take it or make tea out of it nearly every day with benefits that accrue the more you consume it. Gypenoside 49 (49th of the 120 saponins) has been identified as a telomerase activator that youthens us genetically.
4. Ginseng
Known throughout the world for its amazing energy-restoring and strength-building properties, ginseng is an adaptogen that helps our bodies “adapt” to stressful environmental conditions. Ginseng root can boost energy, induce mental alertness and increase endurance. Ginseng also helps fight pain and alleviate radiation damage to healthy tissues.
Known throughout the world for its amazing energy-restoring and strength-building properties, ginseng is an adaptogen that helps our bodies “adapt” to stressful environmental conditions. Ginseng root can boost energy, induce mental alertness and increase endurance. Ginseng also helps fight pain and alleviate radiation damage to healthy tissues.
5. Chlorella
Chlorella is a natural green micro-algae, and a superfood detoxifier. It contains high levels of complete protein with properties that bond with heavy metals and chemical toxins, helping to eliminate them from the brain and nervous system. Chlorella is the highest chlorophyll-containing plant in the world with 40 times the chlorophyll content of the best wheatgrass juice known.
Chlorella is a natural green micro-algae, and a superfood detoxifier. It contains high levels of complete protein with properties that bond with heavy metals and chemical toxins, helping to eliminate them from the brain and nervous system. Chlorella is the highest chlorophyll-containing plant in the world with 40 times the chlorophyll content of the best wheatgrass juice known.
6. Zeolites
Zeolites are a form of unique, volcanic mineral compounds with crystalline structures that form a sort of “cage.” This “cage” works like a magnet to attract heavy metals, chemicals and other pollutants (e.g. radioactive isotopes), capturing them and allowing their easy removal (without being re-absorbed) from the body. Zeolites have been shown to have anti-viral and cancer-fighting effects.
Zeolites are a form of unique, volcanic mineral compounds with crystalline structures that form a sort of “cage.” This “cage” works like a magnet to attract heavy metals, chemicals and other pollutants (e.g. radioactive isotopes), capturing them and allowing their easy removal (without being re-absorbed) from the body. Zeolites have been shown to have anti-viral and cancer-fighting effects.
7. Shilajit
Contains 80+ minerals and fulvic acid which assists in the removal of toxins, improves nutrition to cells and helps restore electricity to the blood. Shilajit promotes the movement of minerals into muscle, tissue and bone. It is an Ayurvedic mineral-herb which translates as the “conqueror of mountains and destroyer of weakness.”
8. Astragalus Root
One of the most potent immune tonics used to improve the lungs, strengthen muscles, increase metabolism, reduce stress and strengthen the genetics. The first telomerase activator product to make it into the market is TA-65, an extract of astragalus.
Contains 80+ minerals and fulvic acid which assists in the removal of toxins, improves nutrition to cells and helps restore electricity to the blood. Shilajit promotes the movement of minerals into muscle, tissue and bone. It is an Ayurvedic mineral-herb which translates as the “conqueror of mountains and destroyer of weakness.”
8. Astragalus Root
One of the most potent immune tonics used to improve the lungs, strengthen muscles, increase metabolism, reduce stress and strengthen the genetics. The first telomerase activator product to make it into the market is TA-65, an extract of astragalus.
9. Camu Camu Berry
This plant-derived Vitamin C source will super-boost your immune system and help repair connective tissue. Camu Camu is one of the most concentrated supplies of Vitamin C in the world, and a powerful antioxidant.
This plant-derived Vitamin C source will super-boost your immune system and help repair connective tissue. Camu Camu is one of the most concentrated supplies of Vitamin C in the world, and a powerful antioxidant.
10. Probiotics
Consuming a combination of good quality probiotics (these include friendly bacteria such as: Lactobacillus acidophilus, Bifidus infantis, B. longum, L. bulgaricus, S. thermophilus, L. plantarum, L. salivarius, Enterococcus faecium, etc.) and cultured and fermented foods like coconut kefir will lead to enhanced immunity as the beneficial probiotic bacteria are symbiotic allies to your body that help: fight viruses, candida and other infections; produce B vitamins; and assist in detoxification. Probiotics help build up that “stress defense shield.”
Consuming a combination of good quality probiotics (these include friendly bacteria such as: Lactobacillus acidophilus, Bifidus infantis, B. longum, L. bulgaricus, S. thermophilus, L. plantarum, L. salivarius, Enterococcus faecium, etc.) and cultured and fermented foods like coconut kefir will lead to enhanced immunity as the beneficial probiotic bacteria are symbiotic allies to your body that help: fight viruses, candida and other infections; produce B vitamins; and assist in detoxification. Probiotics help build up that “stress defense shield.”
When you start investigating and utilizing these substances consistently and regularly, you will notice that your immunity will step-by-step be enhanced. Your thoughts will have more clarity. Your overall energy will increase. You will also likely sleep better and perform better in athletic activities. Your overall productivity will improve. Digestive distress decreases. Feelings of well-being begin to dominate your life.
Superfoods and tonic superherbs can be added into anyone’s diet. Simply begin with the first one or few that you’re drawn to and go from there. Get out a blender and have fun. Make different teas with the superherbs or smoothies with the superfoods. Better yet, take your superherb tea and blend it with your superfoods to make the best elixirs ever. Getting healthier and healthier is fun!
source http://blog.bodymindinstitute.com/
Honey + Apple Cider Vinegar + herbs = medicine
Sep 3, 2014
According to Hippocrates – the father of modern medicine, the combination of vinegar and honey called Oxymel created the foundation for many medicinal herbal formulas as well.
Source: http://mountainroseblog.coms
Oxymels! Oxymel – from the Latin oxymeli meaning “acid and honey” has been made and used in many ways throughout the ages and it’s a recipe that can be adapted to suit your health and herbal needs.
Traditionally, an Oxymel recipe would be used to administer herbs that might not be so pleasant to taste and the more pleasant tasting herbs can become even more tasty after sitting in honey and vinegar. Making your own medicine can be fun and delicious.
After you try making an Oxymel syrup, you can try it in some bubbly water on a warm day, on top of freshly-made pancakes, on a bed of fresh greens from your garden, by itself, or with some warm water to help keep your spirits and throat happy during times of stress.
Use the combination of herbs to aid whatever issues you may be suffering from. Apple cider vinegar and honey alone are a soothing treat to your throat, when you throw in some of your favorite herbs for supporting a healthy functioning immune system you have made Oxymel!
Use the combination of herbs to aid whatever issues you may be suffering from. Apple cider vinegar and honey alone are a soothing treat to your throat, when you throw in some of your favorite herbs for supporting a healthy functioning immune system you have made Oxymel!
An herbal historical combination was created by Rosemary Gladstar, including; ginger, garlic, cayenne, and horseradish and called it fire cider.
What you will need:
- organic apple cider vinegar
- raw local honey
- organic medicinal herbs of your choice (see below)
- pint jar
- pan to decoct
- jar for storage
Notes:
Raw apple cider vinegar is a great way to make an alcohol free extract.
Organic herb possibilities for a throat soothing immune boost:
Generally speaking, you want a ratio of 1:3 – 1:4 .
1 part dried herb to 3 or 4 parts vinegar and honey. You can easily measure by filling a jar less than 1/4 of the way with herbs and then topping with equal parts honey and equal parts vinegar. The older techniques prefer more honey, up to 5 parts honey to 1 parts vinegar, and the newer recipes call for more apple cider vinegar, as much as 3 parts vinegar to one part honey. I prefer half and half. You can find a ratio that suits you! For storage, I prefer a glass jar with a cork top.
1 part dried herb to 3 or 4 parts vinegar and honey. You can easily measure by filling a jar less than 1/4 of the way with herbs and then topping with equal parts honey and equal parts vinegar. The older techniques prefer more honey, up to 5 parts honey to 1 parts vinegar, and the newer recipes call for more apple cider vinegar, as much as 3 parts vinegar to one part honey. I prefer half and half. You can find a ratio that suits you! For storage, I prefer a glass jar with a cork top.
Method 1: Stir, Shake, and Sit
Good method for a variety of herbs!
Place desired herbs into pint jar (1/4 – 1/5 of the way full), cover with apple cider vinegar and honey. You can stir before sealing the jar, or seal the jar and shake until well mixed. Now let your jar sit somewhere cool and dark and shake a couple of times a week. After two weeks, strain and pour into a glass jar for storage.
Method 2: Vinegar Reduction
Great for non-delicate herbs and hearty roots!
If you’re in a pinch and need an Oxymel quickly, you can always experiment with a vinegar reduction. I would not use this method for especially aromatic or floral herbs, as it may be too harsh of an extraction process with heat causing the aromatics to dissipate. In my recipe, it worked well, bringing out the aroma of all herbs perfectly evenly! Apple cider vinegar steam can be very intense, so be careful not to put your face and eyes over the pot while it is simmering (it will not feel good if you do!) You will want to use twice as much vinegar as you need in the end, since this is a reduction and you will loose half of it in the process to evaporation. Reduce for 30-40 minutes on low heat. Once you are done, let cool and strain, mix herbal decocted vinegar with equal parts honey until well mixed and store in an airtight bottle.
Method 3: Infusing Honey and Apple Cider Vinegar Seperately
Nice option for especially delicate herbs.
This is a very easy way to make an Oxymel if you already have infused honey and infused apple cider vinegar, or one or the other. If you have previously infused apple cider vinegar or honey you simply get to mix them together using a ratio that suits you and enjoy! If you regularly cook with herbal infused honeys and vinegars and have some of your favorites sitting around, this can be a great way to turn your culinary spice into a soothing treat!
http://www.happyherbalist.com/
Energising Detoxifying Smoothie
Sep 2, 2014
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My Basic Smoothie (after 1 glass of Kombucha, or Jun, instead of coffee)
Ingredients
use organic when possible
- 1 avocado
- 1 tbs reishi mushroom powder
- 1 tbs hemp seeds (peeled)
- 1 cup coconut milk
- 2 cups water
- 1 cup any leafy greens
- 1 tbs chia seeds
- 1 tbs raw cacao
- 1/4 tbs raw honey
- 1/2 tsp vanilla bean
- 1 tbs cinnamon
- 1 tbs green powder combination with hemp/maca/acai/lucuma/spirulina/cacao
Blend and drink it up! Filling, energizing and detoxifying.
2 Gluten free raw bread alternatives, the sweet and the savory
Aug 22, 2014
The summer has been great, the parties have been fun, my good eating habits sort of crashed. Now its time to get back into feeding my body without the unnecessary crap.....sugar, gluten, and eliminate some dairy products. These foods keep me from feeling my best. Although some of the lyme symptoms can flair, eating right, for me, can be one of my best defences.
Here is how I am getting back on the wagon, starting up the dehydrator again, on the rainy days.
Busy today, with no sun and cool weather it's time to turn on the dehydrator. Its a good day for some savory raw crackers, and a sweet raw banana bread....No sugar, no gluten, no dairy. Just homemade goodness and organic ingredients bring out the best in yourself and feel the love as the good nutrition is absorbed, feed the body, feed the brain, detox.
Beet Carrot Ginger Curcumin Flax Crackers with Nutritional Yeast and Sea Salt.
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the beets make a beautiful color, I spread them thin for a faster drying time. Try to fill up the dehydrator as much as possible in order to save electricity. The raw banana bread is also in.
Here are the finished crackers with my fermented salsa and a cup of kombucha, mmmm.
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Raw Banana Bread
Love this! dehydrate the small loaves over night 8-12 hours depending on how dry or soft you like it........ with flax, dates, raw honey, 4-7 bananas, cinnamon, vanilla, nutmeg, psyllium husk (water if needed). Tomorrows breakfast. This can be frozen for future use. Going in.....JPG)
and finished.....
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a little homemade plum jam will top it off, oh ya!
5-MTHF supplementation, Folate metabolism- getting your energy back
Aug 19, 2014
The Folic Acid Story
methyl-B12, trimethylglycine (TMG), or SAMe may help restore normal ranges (11).
B12, SAMe, TMG
The end product of folate metabolism, 5-MTHF, is an essential precursor for neurotransmitter metabolism and the synthesis of dopamine, serotonin, and norepinephrine. It is also necessary for the production of SAMe, which participates in over 200 enzymatic reactions in the body.
Did the FDA’s attempt to reduce birth defects have unintended consequences? In the 1990’s, the US and UK mandated the enrichment of all grain products with folic acid in hopes of reducing the occurrence of neural tube defects.
In the decades since neural tube defects have indeed declined yet little long term research has been done to determine the effects excess folate might have on non-pregnant adults. The tolerable upper limit (TUL) for folate is set at 1,000 mcg/day for adults, but with the overconsumption of fortified grain products many may exceed this threshold.
Recent studies are now taking a closer look at potential health risks of folic acid fortification for adults. Folate is not only a concern for adults, but may have particular relevance for some people with Chronic Fatigue Syndrome (ME/CFS).
What Role Might folate play in ME/CFS? folate is a vital component of the single carbon pool that participates in basic cellular processes such as amino acid metabolism, synthesis of nucleotides (DNA, RNA, ATP), and methylation (including epigenetic methylation of DNA). Low levels of folate are implicated in increased risk of cardiovascular disease, stroke, dementia, depression, cancers, and birth defects. Similarly, high levels are also associated with carcinogenesis (1). Folate metabolism is a complex, multi-step process that occurs in every cell in the body. It requires three key enzymes: dihydrofolate reductase (DHF), methylenetetrahydrofolate reductase (MTHFR), and methionine synthase (MTR).
When you consume the synthetic form of folate – folic acid – in enriched foods or supplements, it must be converted to different forms utilizing these enzymes. If this conversion is inadequate, functional folic acid deficiencies can emerge that may dampen methylation, amino acid metabolism, etc. Despite the fact that this biochemistry has been known for decades, few studies have examined the exact mechanisms by which folic acid is taken up or metabolized in the body after consumption. Those studies which have examined folic acid metabolism have relied only on mouse models which have substantially different concentrations of the above enzymes than humans (2).
A recent study in patients with stable liver disease indicated, however, that synthetic folic acid from traditional supplements was inefficiently absorbed in the intestinal tract compared to the active 5-methyl-hydrofolate (5-MTHF) form (which was taken up twice as readily). The researchers concluded that food regulatory bodies should rethink their position on folic acid enrichment.
Interestingly, the FDA and European Food Standard Agency have already approved products containing 5-MTHF derivatives to replace folic acid (3).
A Key Metabolic Factor – More Biochemistry
B12, an essential co-factor in folic acid metabolism, is often low in ME/CFS The folate cycle feeds into other key biochemical cycles as well. The end product of folate metabolism, 5-MTHF, is an essential precursor for neurotransmitter metabolism and the synthesis of dopamine, serotonin, and norepinephrine. It is also necessary for the production of SAMe, which participates in over 200 enzymatic reactions in the body.
After 5-MTHF is produced, it is then recycled back into the cycle through the enzyme methionine synthase (MTR). This reaction requires adequate B12 as a cofactor. With B12 deficiency in near epidemic proportions in the elderly, vegetarians, chronic antacid users, SIBO, and people with ME/CFS or FM, it’s possible that folic acid can become trapped as 5-MTHF in what is called the “folate trap.” This “folate trap” prevents the recycling of 5-MTHF back to THF and slows methylation and many other downstream reactions.
Finally, there is a growing understanding of the link between hypothyroidism and proper folate cycle function. Many ME/CFS and FM patients have subclinical hypothyroidism that may be related to inadequate production of 5-MTHF. This methylated form of folate is essential for the conversion of tyrosine to thyroid hormone (1).
Who With ME/CFS or Fibromyalgia Should Be Concerned With This Study? It’s possible but not certain that people with ME/CFS and FM may already be behind the eight ball, so to speak, regarding folate metabolism. Dr. Amy Yasko and the late Rich VonKoynenberg proposed that genetic mutations (single nucleotide polymorphisms or SNPs) in enzymes involved in the folate methylation pathway may be common in the ME/CFS and/or FM populations. Of the three enzymes involved in folate metabolism, methylenetetrahydrofolate reductase (MTHFR) plays the largest role in the conversion and utilization of folates. A genetic defect in this key enzyme could dramatically affect the ability to convert, recycle, and utilize folates.
Genetic Aspects An Open Medicine Institute study is examining the effects of MTHFR mutations on folate metabolism in ME/CFS. Two common genetic variations, C677T and A1298C, have been identified in the MTHFR gene that codes for the MTHFR enzyme. The C677T type has been associated with increased incidence of cardiovascular disease and other health risks (4). This MTHFR SNP has been found to be prevalent in certain populations of people. Heterozygous MTHFR C677T, meaning one copy of the gene is mutated while the other is normal, is found in 42% of Hispanics, 35% of Caucasians, and 14% of African Americans. Homozygotes, where both copies of the gene are mutated, are less common in the general population with 10% preponderance (5).
Further research and stricter study design are certainly warranted. Another study measuring levels of homocysteine in the cerebrospinal fluid of CFS/FM patients found elevations suggestive of problems recycling folate back to methionine. However, it was unclear whether these findings were due to genetic SNPs in enzymes, folate deficiencies, or B12 deficiencies (8).
The Open Medicine Institute is currently engaged in a study to determine the extent of MTHFR mutations and the role they may play in aberrant folate metabolism in ME/CFS.
What Problems Might High Levels of Unmetabolized Folic Acid (UMFA) Pose?
If enzymatic road blocks from genetic mutations or inadequate enzyme cofactors inhibit synthetic folic acid metabolism, high concentrations of folic acid can spill over into the portal circulation. A natural killer connection, of all things, may be possible Elevated levels of unmetabolized folic acid (UMFA) have been implicated in increased overall mortality (9). Epidemiological studies have found a striking association between the incidence of colon cancers and folic acid food enrichment. In the US, rates of colorectal cancer began to increase in 1996 and reached a maximum in 1998. Rates have continued to exceed those present during folic acid pre-enrichment days by as much as 15,000 extra cases per year (2).
Worth mentioning is that these observational studies are inadequate to determine causation due to the inability to control for all possible confounders. Nonetheless, hindsight tells us that careful study of genetic and biochemical factors should have been more thoroughly investigated before implementing a potentially harmful change in food policy.
Some studies also speculate that excess folic acid may be related to decreased natural killer cell cytotoxicity (10). This could be due to the fact that excess naturally occurring folate (DHF) blocks normal function of the MTHFR enzyme providing another potential block in methylation and other downstream biochemical cycles.
More study is urgently needed to determine if synthetic folates hinder immune functioning.
Recommendations for People Who Are Concerned? CFS/FM patients and perhaps everyone should check their methylation status utilizing genetic testing such as 23andMe (see www.23andme.com for $99). Conventional laboratories like Quest or LabCorp also now have MTHFR studies that may be ordered by a healthcare provider. Specialty labs like SpectraCell or HealthDiagnostics specialize in more in-depth methylation studies. (The FDA now allows 23andme to only provide raw data. Several free online tools can, however, do that job. Yasko has an excellent tool plus there’s http://geneticgenie.org/and http://www.promethease.com)
Dietary and Supplementation Suggestions
If MTHFR SNPs are found, consider avoiding all forms of synthetic folate and folic acid—including those found in grain products. (Regardless, avoiding grains due to the high incidence of gluten sensitivity in CFS and FM patients is sometimes recommended.)
Some supplement changes may be in order
Foods high in naturally occurring folate (dihydrofolate, DHF)
spinach, turnip greens, beans, sunflower seeds, Brewer’s yeast, liver.
Foods often fortified with folic acid breakfast cereal, bread, flour, corn meal, pasta, rice. When choosing supplements, opt for a multi-vitamin or B-complex with active forms of folate such as folinic acid or 5-MTHF.
To assess if supplementation is sufficient to bypass methylation defects, routine homocysteine, folate, and B12 can be measured. Folate is most accurately measured as red blood cell folate. Serum B12 measurements are notoriously inaccurate, so methylmalonic acid (MMA) is the preferred test to perform. If MMA is depressed and homocysteine remains high, there may be an additional need for methyl donors to recycle folate through the cycle. Supplemental methyl-B12, trimethylglycine (TMG), or SAMe may help restore normal ranges (11).
Read more: The Folic Acid Controversy, MTHFR and Chronic Fatigue Syndrome http://www.cortjohnson.org/blog/2014/08/12/folic-acid-controversy-mthfr-chronic-fatigue-syndrome/
1 Kelly GS. Folates: Supplemental Forms and Therapeutic Applications. Alt Med Rev 1998. 3(3): p. 208-220. http://www.ncbi.nlm.nih.gov/pubmed/9630738 2 Smith AD, Kim YI, Refsum H. Is folic acid good for everyone? Am J Clin Nutr March 2008 vol. 87 no. 3 517-533. http://www.ncbi.nlm.nih.gov/pubmed/18326588 3 Patanwala I, et al. Folic acid handling by the human gut: implications for food fortification and supplementation. Am J Clin Nutr. 2014 Jun 18;100(2):593-599. [Epub ahead of print]. http://www.ncbi.nlm.nih.gov/pubmed/24944062 4 Klerk M, et al. MTHFR 677C⟶T Polymorphism and Risk of Coronary Heart Disease: A Meta-analysis. JAMA 2002;288:2023-31. http://www.ncbi.nlm.nih.gov/pubmed/12387655 5 Hughes LB et al. Racial or ethnic differences in allele frequencies of single-nucleotide polymorphisms in the methylenetetrahydrofolate reductase gene and their influence on response to methotrexate in rheumatoid arthritis. Ann Rhuem Dis 2006; 65: 1213-1218. http://www.ncbi.nlm.nih.gov/pubmed/16439441 6 Botto Lorenzo, Yang Quanhe. 5,10-Methylenetetrahydrofolate Reductase Gene Variants and Congenital Anomalies: A HuGE Review. Am. J. Epidemiol. 2000; 151(9): 862-877. http://www.ncbi.nlm.nih.gov/pubmed/10791559 7 Regland,B, Andersson M, Abrahamsson L, Bagby J, Dyrehag LE, Gottfries CG. (1997) Increased concentrations of homocysteine in the cerebrospinal fluid in patients with fibromyalgia and chronic fatigue syndrome. Scand J Rheumatol. 26(4):301-7. http://www.ncbi.nlm.nih.gov/pubmed/9310111 8 Harmon DL, McMaster D, McCluskey DR, Shields D, Whitehead AS. (1997) A common genetic variant affecting folate metabolism is not over-represented in chronic fatigue syndrome. Ann Clin Biochem. 34 (Pt 4):427-9. http://www.ncbi.nlm.nih.gov/pubmed/9247678 9 Neuhouser ML, et al. Mathematical modeling predicts the effect of folate deficiency and excess on cancer-related biomarkers. Cancer Epidemiol Biomarkers Prev. 2011 Sep;20(9):1912-7. Epub 2011 Jul 13. http://www.ncbi.nlm.nih.gov/pubmed/21752986 10 Troen AM, et al. Unmetabolized folic acid in plasma is associated with reduced natural killer cell cytotoxicity among postmenopausal women. J Nutr. 2006 Jan;136(1):189-94. http://www.ncbi.nlm.nih.gov/pubmed/16365081 11 Olthof Margreet, Trinette van Vliet, Esther Boelsma, Petra Verhoef. Low Dose Betaine Supplementation Leads to Immediate and Long Term Lowering of Plasma Homocysteine in Healthy Men and Women. J. Nutr. 2003 Dec. 1; 133(12): 4135-4138. http://www.ncbi.nlm.nih.gov/pubmed/14652361
methyl-B12, trimethylglycine (TMG), or SAMe may help restore normal ranges (11).
The end product of folate metabolism, 5-MTHF, is an essential precursor for neurotransmitter metabolism and the synthesis of dopamine, serotonin, and norepinephrine. It is also necessary for the production of SAMe, which participates in over 200 enzymatic reactions in the body.
Did the FDA’s attempt to reduce birth defects have unintended consequences? In the 1990’s, the US and UK mandated the enrichment of all grain products with folic acid in hopes of reducing the occurrence of neural tube defects.
In the decades since neural tube defects have indeed declined yet little long term research has been done to determine the effects excess folate might have on non-pregnant adults. The tolerable upper limit (TUL) for folate is set at 1,000 mcg/day for adults, but with the overconsumption of fortified grain products many may exceed this threshold.
Recent studies are now taking a closer look at potential health risks of folic acid fortification for adults. Folate is not only a concern for adults, but may have particular relevance for some people with Chronic Fatigue Syndrome (ME/CFS).
What Role Might folate play in ME/CFS? folate is a vital component of the single carbon pool that participates in basic cellular processes such as amino acid metabolism, synthesis of nucleotides (DNA, RNA, ATP), and methylation (including epigenetic methylation of DNA). Low levels of folate are implicated in increased risk of cardiovascular disease, stroke, dementia, depression, cancers, and birth defects. Similarly, high levels are also associated with carcinogenesis (1). Folate metabolism is a complex, multi-step process that occurs in every cell in the body. It requires three key enzymes: dihydrofolate reductase (DHF), methylenetetrahydrofolate reductase (MTHFR), and methionine synthase (MTR).
When you consume the synthetic form of folate – folic acid – in enriched foods or supplements, it must be converted to different forms utilizing these enzymes. If this conversion is inadequate, functional folic acid deficiencies can emerge that may dampen methylation, amino acid metabolism, etc. Despite the fact that this biochemistry has been known for decades, few studies have examined the exact mechanisms by which folic acid is taken up or metabolized in the body after consumption. Those studies which have examined folic acid metabolism have relied only on mouse models which have substantially different concentrations of the above enzymes than humans (2).
A recent study in patients with stable liver disease indicated, however, that synthetic folic acid from traditional supplements was inefficiently absorbed in the intestinal tract compared to the active 5-methyl-hydrofolate (5-MTHF) form (which was taken up twice as readily). The researchers concluded that food regulatory bodies should rethink their position on folic acid enrichment.
Interestingly, the FDA and European Food Standard Agency have already approved products containing 5-MTHF derivatives to replace folic acid (3).
A Key Metabolic Factor – More Biochemistry
B12, an essential co-factor in folic acid metabolism, is often low in ME/CFS The folate cycle feeds into other key biochemical cycles as well. The end product of folate metabolism, 5-MTHF, is an essential precursor for neurotransmitter metabolism and the synthesis of dopamine, serotonin, and norepinephrine. It is also necessary for the production of SAMe, which participates in over 200 enzymatic reactions in the body.
After 5-MTHF is produced, it is then recycled back into the cycle through the enzyme methionine synthase (MTR). This reaction requires adequate B12 as a cofactor. With B12 deficiency in near epidemic proportions in the elderly, vegetarians, chronic antacid users, SIBO, and people with ME/CFS or FM, it’s possible that folic acid can become trapped as 5-MTHF in what is called the “folate trap.” This “folate trap” prevents the recycling of 5-MTHF back to THF and slows methylation and many other downstream reactions.
Finally, there is a growing understanding of the link between hypothyroidism and proper folate cycle function. Many ME/CFS and FM patients have subclinical hypothyroidism that may be related to inadequate production of 5-MTHF. This methylated form of folate is essential for the conversion of tyrosine to thyroid hormone (1).
Who With ME/CFS or Fibromyalgia Should Be Concerned With This Study? It’s possible but not certain that people with ME/CFS and FM may already be behind the eight ball, so to speak, regarding folate metabolism. Dr. Amy Yasko and the late Rich VonKoynenberg proposed that genetic mutations (single nucleotide polymorphisms or SNPs) in enzymes involved in the folate methylation pathway may be common in the ME/CFS and/or FM populations. Of the three enzymes involved in folate metabolism, methylenetetrahydrofolate reductase (MTHFR) plays the largest role in the conversion and utilization of folates. A genetic defect in this key enzyme could dramatically affect the ability to convert, recycle, and utilize folates.
Genetic Aspects An Open Medicine Institute study is examining the effects of MTHFR mutations on folate metabolism in ME/CFS. Two common genetic variations, C677T and A1298C, have been identified in the MTHFR gene that codes for the MTHFR enzyme. The C677T type has been associated with increased incidence of cardiovascular disease and other health risks (4). This MTHFR SNP has been found to be prevalent in certain populations of people. Heterozygous MTHFR C677T, meaning one copy of the gene is mutated while the other is normal, is found in 42% of Hispanics, 35% of Caucasians, and 14% of African Americans. Homozygotes, where both copies of the gene are mutated, are less common in the general population with 10% preponderance (5).
Further research and stricter study design are certainly warranted. Another study measuring levels of homocysteine in the cerebrospinal fluid of CFS/FM patients found elevations suggestive of problems recycling folate back to methionine. However, it was unclear whether these findings were due to genetic SNPs in enzymes, folate deficiencies, or B12 deficiencies (8).
The Open Medicine Institute is currently engaged in a study to determine the extent of MTHFR mutations and the role they may play in aberrant folate metabolism in ME/CFS.
What Problems Might High Levels of Unmetabolized Folic Acid (UMFA) Pose?
If enzymatic road blocks from genetic mutations or inadequate enzyme cofactors inhibit synthetic folic acid metabolism, high concentrations of folic acid can spill over into the portal circulation. A natural killer connection, of all things, may be possible Elevated levels of unmetabolized folic acid (UMFA) have been implicated in increased overall mortality (9). Epidemiological studies have found a striking association between the incidence of colon cancers and folic acid food enrichment. In the US, rates of colorectal cancer began to increase in 1996 and reached a maximum in 1998. Rates have continued to exceed those present during folic acid pre-enrichment days by as much as 15,000 extra cases per year (2).
Worth mentioning is that these observational studies are inadequate to determine causation due to the inability to control for all possible confounders. Nonetheless, hindsight tells us that careful study of genetic and biochemical factors should have been more thoroughly investigated before implementing a potentially harmful change in food policy.
Some studies also speculate that excess folic acid may be related to decreased natural killer cell cytotoxicity (10). This could be due to the fact that excess naturally occurring folate (DHF) blocks normal function of the MTHFR enzyme providing another potential block in methylation and other downstream biochemical cycles.
More study is urgently needed to determine if synthetic folates hinder immune functioning.
Recommendations for People Who Are Concerned? CFS/FM patients and perhaps everyone should check their methylation status utilizing genetic testing such as 23andMe (see www.23andme.com for $99). Conventional laboratories like Quest or LabCorp also now have MTHFR studies that may be ordered by a healthcare provider. Specialty labs like SpectraCell or HealthDiagnostics specialize in more in-depth methylation studies. (The FDA now allows 23andme to only provide raw data. Several free online tools can, however, do that job. Yasko has an excellent tool plus there’s http://geneticgenie.org/and http://www.promethease.com)
Dietary and Supplementation Suggestions
If MTHFR SNPs are found, consider avoiding all forms of synthetic folate and folic acid—including those found in grain products. (Regardless, avoiding grains due to the high incidence of gluten sensitivity in CFS and FM patients is sometimes recommended.)
Some supplement changes may be in order
Foods high in naturally occurring folate (dihydrofolate, DHF)
spinach, turnip greens, beans, sunflower seeds, Brewer’s yeast, liver.
Foods often fortified with folic acid breakfast cereal, bread, flour, corn meal, pasta, rice. When choosing supplements, opt for a multi-vitamin or B-complex with active forms of folate such as folinic acid or 5-MTHF.
To assess if supplementation is sufficient to bypass methylation defects, routine homocysteine, folate, and B12 can be measured. Folate is most accurately measured as red blood cell folate. Serum B12 measurements are notoriously inaccurate, so methylmalonic acid (MMA) is the preferred test to perform. If MMA is depressed and homocysteine remains high, there may be an additional need for methyl donors to recycle folate through the cycle. Supplemental methyl-B12, trimethylglycine (TMG), or SAMe may help restore normal ranges (11).
Read more: The Folic Acid Controversy, MTHFR and Chronic Fatigue Syndrome http://www.cortjohnson.org/blog/2014/08/12/folic-acid-controversy-mthfr-chronic-fatigue-syndrome/
1 Kelly GS. Folates: Supplemental Forms and Therapeutic Applications. Alt Med Rev 1998. 3(3): p. 208-220. http://www.ncbi.nlm.nih.gov/pubmed/9630738 2 Smith AD, Kim YI, Refsum H. Is folic acid good for everyone? Am J Clin Nutr March 2008 vol. 87 no. 3 517-533. http://www.ncbi.nlm.nih.gov/pubmed/18326588 3 Patanwala I, et al. Folic acid handling by the human gut: implications for food fortification and supplementation. Am J Clin Nutr. 2014 Jun 18;100(2):593-599. [Epub ahead of print]. http://www.ncbi.nlm.nih.gov/pubmed/24944062 4 Klerk M, et al. MTHFR 677C⟶T Polymorphism and Risk of Coronary Heart Disease: A Meta-analysis. JAMA 2002;288:2023-31. http://www.ncbi.nlm.nih.gov/pubmed/12387655 5 Hughes LB et al. Racial or ethnic differences in allele frequencies of single-nucleotide polymorphisms in the methylenetetrahydrofolate reductase gene and their influence on response to methotrexate in rheumatoid arthritis. Ann Rhuem Dis 2006; 65: 1213-1218. http://www.ncbi.nlm.nih.gov/pubmed/16439441 6 Botto Lorenzo, Yang Quanhe. 5,10-Methylenetetrahydrofolate Reductase Gene Variants and Congenital Anomalies: A HuGE Review. Am. J. Epidemiol. 2000; 151(9): 862-877. http://www.ncbi.nlm.nih.gov/pubmed/10791559 7 Regland,B, Andersson M, Abrahamsson L, Bagby J, Dyrehag LE, Gottfries CG. (1997) Increased concentrations of homocysteine in the cerebrospinal fluid in patients with fibromyalgia and chronic fatigue syndrome. Scand J Rheumatol. 26(4):301-7. http://www.ncbi.nlm.nih.gov/pubmed/9310111 8 Harmon DL, McMaster D, McCluskey DR, Shields D, Whitehead AS. (1997) A common genetic variant affecting folate metabolism is not over-represented in chronic fatigue syndrome. Ann Clin Biochem. 34 (Pt 4):427-9. http://www.ncbi.nlm.nih.gov/pubmed/9247678 9 Neuhouser ML, et al. Mathematical modeling predicts the effect of folate deficiency and excess on cancer-related biomarkers. Cancer Epidemiol Biomarkers Prev. 2011 Sep;20(9):1912-7. Epub 2011 Jul 13. http://www.ncbi.nlm.nih.gov/pubmed/21752986 10 Troen AM, et al. Unmetabolized folic acid in plasma is associated with reduced natural killer cell cytotoxicity among postmenopausal women. J Nutr. 2006 Jan;136(1):189-94. http://www.ncbi.nlm.nih.gov/pubmed/16365081 11 Olthof Margreet, Trinette van Vliet, Esther Boelsma, Petra Verhoef. Low Dose Betaine Supplementation Leads to Immediate and Long Term Lowering of Plasma Homocysteine in Healthy Men and Women. J. Nutr. 2003 Dec. 1; 133(12): 4135-4138. http://www.ncbi.nlm.nih.gov/pubmed/14652361
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